Runners-up in 2019 and 2022, the Blaugranes were chasing their third consecutive Champions League title and their fourth in five years
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Arsenal meanwhile failed to make the final for the second time 19 years after their debut there in 2006, when they lost against FC Barcelona.
The Gunners were ruthless, punishing errors from the eight-time Champions League winners and turning them into goals.
Scheduled for Wednesday at the Santiago Bernabeu, the game will see Madrid attempt to wipe out the 0-3 deficit suffered at the Emirates last week in what will require a staggering attacking performance. Arsenal go into the game with comfort and could adopt a safety-first approach that preserves their three-goal advantage.
The result of the midweek match meant the Gunners moved back into second place in the English Premier League.
Arsenal will host Newcastle United in the first leg at the Emirates Stadium on Tuesday, while Liverpool travel to the Tottenham Hotspur Stadium on Wednesday. Both matches will be broadcast live on GOtv Channel 65 at 9 PM.
The result against Brentford ensured that they moved back into second place in the English Premier League on Wednesday.
The hosts should have been further ahead before halftime with Forest keeper Matz Sels making several fine saves to keep his side in it.
Following their 1-0 defeat at Newcastle, Chelsea leapfrogged Arsenal to fourth position last week courtesy of their 1-1 draw at Old Trafford.
After drawing away to Italian side Atalanta in their opening game the onus was on Mikel Arteta’s side to deliver a home win against last year’s semi-finalists and they delivered.
The Gunners had looked like clinging on for victory having played the entire second half at the Etihad Stadium with 10 men.
Week 2 Premier League action will kick off at AMEX Stadium, where Brighton and Hove Albion will host Manchester United.
“I knew this was an exciting opportunity for me, I know I can bring a lot to the team,” Nwakali told the club’s official website
The erstwhile skipper of Nigeria senior national team marked his 48th year birthday on Thursday.
The Nigeria international is expected to leave Naples this summer with Paris Saint-Germain leading the race to sign the striker last month.
The Nigerian striker, 25, is expected to leave Naples this summer after hinting that he had “made a decision on his next step” back in January.
Arsenal have 77 points from 34 games with Liverpool, who face Everton on Wednesday, on 74 from 33
The English Premier League London derby match will be broadcast live on GOtv today (Tuesday).
In a tight and cagey second leg, Gabriel Martinelli had Arsenal’s best chance of the first half but shot straight at Manuel Neuer
Arsenal were stunned as their former striker Serge Gnabry levelled six minutes later and Kane rolled home his 39th goal