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Home»R&D Health»Men with large breasts at higher risk of breast cancer – Expert
R&D Health

Men with large breasts at higher risk of breast cancer – Expert

Adeola BalogunBy Adeola BalogunApril 12, 2025No Comments
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Dr Uche Nwokwu, Coordinator of the National Cancer Control Programme, Ministry of Health and Social Welfare, says men with large breasts are at a higher risk of developing breast cancer.

Nwokwu revealed this in an interview with the News Agency of Nigeria on Saturday in Abuja.

He said that men undergoing hormone therapy to alter their body physiology to appear more feminine are also at elevated risk.

He explained that because men had breast tissue, they could develop breast cancer, although the condition was rare.

Confirming that such cases had been recorded in Nigeria, the NCCP coordinator emphasised the need for awareness.

According to him, breast development in men can be triggered by an increase in estrogen, the hormone responsible for breast growth, particularly when testosterone levels drop.

He said: “The hormone that women have that makes their breasts develop is also present in men.

“The difference is that testosterone, which is higher in men, suppresses that hormone;  so, when there’s an imbalance between the two, whichever is higher tends to manifest more.”

He added that when estrogen levels in men become dominant, it could lead to gynecomastia (the enlargement of male breast tissue) which in turn increases the risk of breast cancer.

“Once there’s a fluctuation that disrupts the body’s ability to regulate the cell ducts, it can trigger breast cancer,” he said.

Nwokwu noted that the risk factors for breast cancer in men are similar to those in women.

He, however, said that women were more prone due to their more developed breast tissue and cell ducts.

He said that men with larger breasts face a higher risk than those with average breast size, though no man was completely exempted.

“The reason is simple, anything that lowers male hormones, whether due to sickness or environmental factors, can cause an increase in female hormones.

“That imbalance can result in gynecomastia and, by extension, raise the risk of breast cancer,” he said.

He also identified genetics as a significant factor, saying “people who come from families with a genetic predisposition need to be cautious, as even slight environmental triggers can elevate their risk.”

The coordinator further warned that men who undergo hormone therapy in attempts to transition to a female body structure are also at increased risk.

“When men take hormone therapies to alter their physiology, the more active female hormones can expose them to a higher risk of breast cancer,” he said.

On available data, Nwokwu said figures are low partly because men often do not recognise the symptoms of breast cancer until they receive a proper diagnosis.

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He acknowledged the lack of conclusive data on the disease in men, saying it reflected a broader challenge in cancer data collection.

However, the NCCP coordinator noted that the Federal Government had designated cancer as a reportable disease to enhance data gathering.

He added that efforts were underway to improve diagnostic capacity nationwide, so that any abnormality found in the body could be accurately identified and diagnosed.

To reduce the risk of breast cancer, Nwokwu advised men to regularly check their bodies for lumps or unusual growths, especially in the breast area.

“Any abnormal growth should be properly investigated. Tissue samples should be taken for laboratory diagnosis,” he advised.

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