The Blades will return to the Premier League after two seasons, having been relegated in the 2020-21 campaign in which they finished bottom of the table.
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The Clarets, unbeaten in the league since November, took an early lead when Ashley Barnes redirected Josh Brownhill’s low shot into the back of the net.
The attacking midfielder has enjoyed a promising first season in the Premier League following his arrival from QPR in August 2020 in a deal worth £20 million.
Red Devils skipper, Harry Maguire, Anthony Martial, Marcus Rashford and Nemanja Matic were preferred substitutes ahead of Ighalo in the tie
The Reds winger netted from the edge of the box in spectacular fashion in both halves, to cancel out a fine strike from Rhian Brewster and a controversial penalty by Andre Ayew.
Prize guy Semi Ajayi dedicated his award to his Rotherham United teammates after being named Sky Bet Championship Player of the Month for March.
The Sky Bet Championship club announced last week the 31-year-old had begun immediate treatment after being diagnosed with the disease during pre-season training.
The move comes after The FA was criticised for punishing players for betting violations while having deals in place with gambling companies
Trailing by two points in the final day to Brighton & Hove Albion, the Rafa Benitez boys eased past Barnsley 3-0, although they have Aston Villa to thank for the achievement