Alvaro Morata gave Atletico an early lead against Sociedad as he tapped home in the 5th minute following a near post corner from Yannick Carrasco that was not claimed by Alex Remiro.
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The win helped them to tighten their grip on fourth place in La Liga.
Kylian Mbappe scored four goals to help World Cup titleholders France secure an 8-0 home demolition of Kazakhstan.
The 26-year-old left the Spanish capital for the Chinese Super League in February 2018 in a double deal with teammate Nicolas Gaitan but has been actively seeking a return to European football over the last few months.
An eye-catching volley from Dries Mertens ended Panama’s resistance two minutes after the restart, and Manchester United striker Lukaku followed with two tidy finishes of his own to make the scoreline more convincing