Marcus Rashford added to an early Bruno Fernandes penalty to send the Red Devils two goals ahead just past the hour.
Browsing: Jeffrey Schlupp
The quartet are among a host of other players, including Bayer Leverkusen forward Callum Hudson-Odoi.
The attacker, 19, rifled home at the second attempt shortly past the hour mark to put the Eagles back in the contest after first-half strikes by Kelechi Iheanacho and Jamie Vardy.
Roy Hodgson’s side had not tasted success since thrashing West Brom at the start of December but two first-half goals coupled with a professional display helped them to triumph in their first match of the year.
The Nigerian-born midfielder starred for minutes as second half substitute, replacing Jeffrey Schlupp in a match they won by a lone goal.
Crystal Palace moved further away from the Premier League relegation zone with a 3-1 win at fellow strugglers Burnley on Saturday.
Fulham thus became the first side in top-flight history to lose eight successive London derbies