Jon Gorenc Stankovic - making his first appearance in 17 months due to a knee injury sustained at this ground - netted Huddersfield's consolation goal
Chelsea manager Antonio Conte opted for Davide Zappacosta, Cesc Fabregas, N’Golo Kante and Marcos Alonso for the midfield role.
City, who lifted the Premier League trophy in front of their fans after the match, mustered only two shots on target all game, as relegation-threatened Huddersfield dug in for a vital point.
The Red Devils, who topped Deloitte’s Money League in January for the world’s richest clubs, also came out top of the Social Network Rankings for the English Premier League in 2017
The Spaniard took charge of Newcastle United in 2016 and helped them earn promotion from the Championship last season.
Jose Mourinho's side are still three points clear of third-placed Liverpool and indeed fourth-placed Chelsea, but the defeat at Tottenham was a reality check for a team that still has a lot to work on in the final months of the campaign
German midfielder Emre Can fired the visitors ahead in the 26th minute with a fine first-time effort from 25 metres which took a slight deflection to beat goalkeeper Jonas Loss