Frank Lampard’s side would jump from fifth to first with victory in the opening match of gameweek nine, but they have struggled at this venue in recent seasons.
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His miss came in their 4-0 win over Russian side Krasnodar in the UEFA Champions League on Wednesday.
Jorginho missed a penalty for Chelsea but Callum Hudson-Odoi put the Blues in front before half-time after a mistake by Krasnodar goalkeeper Matvei Safonov.
United, who had lost their opening two home games of the season, have seven points from five games and are 15th on the table, while Chelsea are in sixth position with nine points from six games.
The Red Devils go into the match off the back of a memorable Champions League triumph in Paris, while Chelsea were held to a goalless draw by Sevilla in midweek.
It was the first 0-0 draw for Chelsea since Lampard took charge before last season.
Just one point separates the two sides in the table after four games of the season, and both teams head into this contest off the back of victories before the two-week stoppage.
The 22-year-old England international saw his stock rise greatly during a previous loan, working under Frank Lampard in 2018/19, and he’s decided to stay at Stamford Bridge and continue his development under the Blues legend this season.
The 29-year-old will join the Russian side on a temporary switch until the end of the campaign.
Frank Lampard’s side were forced to pull off a three-goal comeback at West Bromwich Albion last weekend before being knocked out of the EFL Cup in midweek, while Palace are also looking to bounce back from a defeat
The former Super Eagles star returned to West London this month after his brief loan stint at Inter Milan and he is yet to make a matchday squad since the start of the campaign.
The striker scored an injury-time leveller to rescue a 3-3 draw and cap the visitors’ excellent fightback from 3-0 down.
The Baggies have lost their first two games back in the top flight and were knocked out of the EFL Cup in midweek, whereas Chelsea have won and lost their opening two league games.
The former England international said he has now understood that it was important for the Premier League to help out.
Tomori came off the bench after Andreas Christensen’s red card for his first Blues outing in seven months on Sunday, as Sadio Mane’s brace sealed Liverpool’s Premier League win.
Tomori has been heavily linked with a loan switch to Everton, with the Toffees understood to be keen to take the 22-year-old to Goodison Park for the season.
Anjorin will leave Stamford Bridge only on one condition – unless he gets a loan offer that’s too good to refuse.
The 35-year-old has signed a one-year Stamford Bridge contract, with the club holding the option of adding another 12 months
The German guided the Reds to their first Premier League title in an historic season for the Merseyside club. It ended a 30-year wait for a top-flight title.
The former England international said his players run the risk of sustaining injuries, given the short turnaround between campaigns.