Franco Vazquez put Sevilla ahead at Rayo in the 15th minute after each side had goals correctly ruled out for offside without using VAR
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The visitors began brightly as Mats Hummels and Thomas Muller sent efforts wide of target in the opening 10 minutes
Barca, who played an hour without the benched Messi, could see their lead at the top of the table reduced to nine points if Atletico Madrid beat relegation-threatened Deportivo La Coruna on Sunday night