Neymar limped out of Brazil’s friendly against Nigeria in Singapore on Sunday after only 12 minutes.
The 27-year-old was replaced by midfielder Philippe Coutinho after feeling an injury in his left thigh.
The match was 0-0 after 30 minutes.
Paris Saint-Germain star Neymar missed this year’s Copa America because of a right ankle injury.
He only returned to action two months later.
The Brazilian also had a right foot injury in January playing for PSG.
The problem in his fifth metatarsal kept him off the pitch for almost three months.
Neymar also injured his right foot months before the World Cup in Russia in 2018.
The friendly could have marked Neymar’s rise to second all-time Brazil top goal scorer.
He has 61 goals, one less than two-time World Cup winner Ronaldo.