Three-time African champions, Super Eagles, will aim at consolidating on their 1-0 victory over Poland in Tuesday’s friendly against Serbia in London.
Serbia, on the other hand, are looking to regain some pride after losing to Morocco last week.
With Nigeria facing Croatia in Group D of the World Cup in Russia, there is a sort of logic behind this fixture.
Whether or not it makes any meaningful difference remains to be seen, but either way, this will offer both sides a good test going into the summer.
Serbia will be disappointed after they failed to get a result in a tense match with Morocco.
The home side, who had only lost once in their previous 10 games before the fall to Morocco, will need to see a vast improvement before June as they have one of the tougher groups, consisting of Costa Rica, Switzerland and most worryingly, Brazil.
The impressive victory means that Nigeria have now won five out of their last six matches in all competitions.
Serbia head coach Mladen Krstajic may look to experiment after his side fell to Morocco last week, with the option to include Cardiff City midfielder Marko Grujic a possibility to add more attacking capabilities into the midfield.