Pope Francis has begun a trip to Egypt expected to focus on peace and dialogue with Islam against the backdrop of increasing attacks against the country’s Christian minority.
The pontiff’s plane took off at around 11am (0900 GMT) from Rome’s Fiumicino airport, live TV coverage showed.
It was expected to land in Cairo at 1200 GMT.
Meanwhile, in Cairo, tight security measures have been imposed and welcoming banners were placed across Cairo carrying the motto for the trip: “Pope of Peace in Egypt of Peace.”
Francis is scheduled to meet with President Abdel-Fattah al-Sissi and Coptic Orthodox Pope Tawadros II.
He will address an international peace conference at al-Azhar, the world’s foremost seat of Sunni Islamic theology, hosted by Ahmed al-Tayeb, the Grand Imam of the institution.
On Saturday, he will hold a mass at the military-run Air Defence Stadium, on the outskirts of Cairo, before meeting with Egyptian Catholic church leaders.
Francis becomes the second Vatican leader to visit mostly Muslim Egypt, after John Paul II visited in 2000.
His trip comes weeks after the April 9 suicide bombings at two Coptic churches killed at least 46 people on Palm Sunday.
The attacks were claimed by the Islamic State extremist militia.
Christians are among the oldest religious communities in the Middle East, but their numbers have dwindled in the face of wars and persecution.
Egypt has the largest Christian community in the region, accounting for around 10 per cent of the country’s 92 million population.
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